Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbbp8nlRetinoblastoma binding protein 8-like. (588 aa)    
Predicted Functional Partners:
cdk5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
    
 0.817
DLK1
Delta like non-canonical Notch ligand 1.
    
   0.572
ccna2
Cyclin A2; Belongs to the cyclin family.
     
 0.537
Ccna1
Cyclin A1; Belongs to the cyclin family.
     
 0.537
LOC103025715
Fibroblast growth factor (acidic) intracellular binding protein b.
    
 
 0.513
fibp
Fibroblast growth factor (acidic) intracellular binding protein a.
    
 
 0.513
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.482
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.482
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.482
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.482
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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