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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sox13SRY-box transcription factor 13. (647 aa)    
Predicted Functional Partners:
cep85
Centrosomal protein 85.
    
 
 0.634
Sox5
SRY-box transcription factor 5.
    
 
0.606
Trip12
Thyroid hormone receptor interactor 12.
    
 
 0.509
ENSAMXP00000039594
Uncharacterized protein.
    
 
 0.509
LOC103034575
Catenin, beta 2.
   
 0.476
W5KDJ8_ASTMX
Junction plakoglobin b.
   
 0.476
LOC103045821
Junction plakoglobin a.
   
 0.476
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.476
LOC103022374
Transcription factor 7 like 1b.
     
0.459
W5L9B2_ASTMX
Transcription factor 7.
     
0.459
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.