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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nlgn2Neuroligin 2a. (829 aa)    
Predicted Functional Partners:
W5JY99_ASTMX
Neurexin 1b.
    
 0.956
nrxn3
Neurexin 3a.
    
 0.825
ENSAMXP00000045941
Uncharacterized protein.
    
 0.741
LOC103024923
Neurexin 2a.
    
 0.741
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1.
   
 0.587
NRXN1
Neurexin 1.
    
 0.579
W5L097_ASTMX
Neurexin 3b.
    
 0.579
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2a.
   
 0.566
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2.
   
 0.566
wdr43
WD repeat domain 43.
   
 0.565
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.