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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103034907Cholinergic receptor, nicotinic, beta 1 (muscle) like. (495 aa)    
Predicted Functional Partners:
LOC103042886
Cholinergic receptor, nicotinic, alpha 1 (muscle).
  
0.766
W5JZQ7_ASTMX
Cholinergic receptor, nicotinic, alpha 2a (neuronal).
  
 
0.705
LOC103025036
Cholinergic receptor, nicotinic, alpha 4b.
  
 
0.702
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
0.649
LOC103030483
Cholinergic receptor, nicotinic, alpha 7 (neuronal).
   
0.592
LOC103031133
Cholinergic receptor, nicotinic, alpha 2b (neuronal).
  
 
0.558
LOC103031723
Cholinergic receptor, nicotinic, beta 3b (neuronal).
  
0.554
W5LJM4_ASTMX
Cholinergic receptor, nicotinic, beta polypeptide 3a.
  
0.553
W5K0V1_ASTMX
Si:ch73-380n15.2.
  
0.407
W5KRB2_ASTMX
Si:ch211-39a7.1.
  
0.406
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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