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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mgat5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (733 aa)    
Predicted Functional Partners:
mgat4c
Mgat4 family member C.
   
 
 0.952
Mgat4b
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B.
     
 0.949
mgat4d
Zgc:154054.
     
 0.936
mgat4a
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A.
   
 
 0.936
LOC103036431
Zgc:101663.
     
  0.901
W5L930_ASTMX
Uncharacterized protein.
  
  
 
0.901
LOC103023235
Survival of motor neuron 1, telomeric.
    
 
 0.649
rnpc3
RNA-binding region (RNP1, RRM) containing 3.
    
 
 0.649
gemin5
Gem (nuclear organelle) associated protein 5.
     
 0.625
hspa13
Heat shock protein 70 family, member 13.
   
 0.607
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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