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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zdhhc7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (300 aa)    
Predicted Functional Partners:
wrn
WRN RecQ like helicase.
    
 0.538
pot1
Protection of telomeres 1 homolog.
    
 0.517
LOC103043741
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
  0.457
W5KLY7_ASTMX
Estrogen receptor 2b.
    
  0.457
LOC103028984
Estrogen receptor 2a.
    
  0.457
rad50
RAD50 homolog, double strand break repair protein.
    
 0.426
ENSAMXP00000045394
Golgin A7.
    
 0.420
ENSAMXP00000050623
Golgin A7.
    
 0.420
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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