close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Col4a1Collagen, type IV, alpha 1. (1264 aa)    
Predicted Functional Partners:
Itga1
Integrin, alpha 1; Belongs to the integrin alpha chain family.
     
 0.706
W5K1Q3_ASTMX
Integrin beta; Belongs to the integrin beta chain family.
    
 0.705
LOC103043996
Integrin beta; Belongs to the integrin beta chain family.
    
 0.705
itgb5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.705
LOC103032002
Integrin, alpha 3a; Belongs to the integrin alpha chain family.
    
 0.702
LOC103040573
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
    
 0.702
LOC103047301
Integrin beta; Belongs to the integrin beta chain family.
    
 0.698
W5KYE2_ASTMX
Integrin beta; Belongs to the integrin beta chain family.
    
 0.698
itgb4
Integrin beta.
    
 0.698
LOC103030260
Integrin beta; Belongs to the integrin beta chain family.
    
 0.698
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.