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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wee1Wee1-like protein kinase. (616 aa)    
Predicted Functional Partners:
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.976
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 0.915
wee2
Wee1-like protein kinase.
  
  
 
0.903
WEE1
WEE1 G2 checkpoint kinase; Belongs to the protein kinase superfamily.
  
  
 
0.901
chek1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
0.847
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.833
chek2
Checkpoint kinase 2.
   
 
0.806
cntd2
Cyclin N-terminal domain containing 2; Belongs to the cyclin family.
   
 0.789
LOC103043733
Cyclin B2; Belongs to the cyclin family.
   
 0.789
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
0.777
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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