close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103024192Aurora kinase B; Belongs to the protein kinase superfamily. (318 aa)    
Predicted Functional Partners:
W5L3Y7_ASTMX
INCENP_N domain-containing protein.
   
 0.988
W5KDD8_ASTMX
TPX2 microtubule nucleation factor.
   
 0.963
cdca8
Cell division cycle associated 8.
   
 0.960
ndc80
NDC80 kinetochore complex component.
   
 
 0.934
ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.926
birc5
Baculoviral IAP repeat containing 5a.
   
 0.918
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.918
Birc6
Baculoviral IAP repeat containing 6.
   
 0.916
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.916
ENSAMXP00000040314
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.916
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (36%) [HD]