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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOX4NADPH oxidase 4. (481 aa)    
Predicted Functional Partners:
LOC103041742
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.920
ncf1
Neutrophil cytosolic factor 1.
   
 0.838
ncf4
Neutrophil cytosolic factor 4.
   
 0.771
ncf2
Neutrophil cytosolic factor 2.
   
 0.751
LOC103025255
NADPH oxidase organizer 1a.
   
 0.748
ENSAMXP00000049007
NADPH oxidase activator 1.
   
 0.722
LOC103028223
Dual oxidase 2.
   
 
 0.695
LOC103031151
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
  
 
0.687
nox1
NADPH oxidase 1.
  
 
0.685
LOC103036070
NADPH oxidase organizer 1b.
   
 0.656
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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