Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rps6ka2Ribosomal protein S6 kinase. (733 aa)    
Predicted Functional Partners:
W5KTH2_ASTMX
TSC complex subunit 2.
    
 0.973
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.970
LOC103041389
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.970
atf4
Activating transcription factor 4a.
    
 0.965
LOC103040096
TBC1 domain family, member 7.
     
 0.957
pkmyt1
Protein kinase, membrane associated tyrosine/threonine 1.
     
  0.952
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
     
  0.945
W5KMM6_ASTMX
TSC complex subunit 1b.
    
 0.943
tsc1
TSC complex subunit 1a.
    
 0.905
ENSAMXP00000045273
Ribosomal protein S6 kinase.
     
  0.805
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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