close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
McuMitochondrial calcium uniporter. (277 aa)    
Predicted Functional Partners:
micu1
Mitochondrial calcium uptake 1.
    
 0.963
W5KH13_ASTMX
Mitochondrial calcium uptake 2.
    
 0.921
LOC103023443
Single-pass membrane protein with aspartate-rich tail 1b.
    
 0.914
smdt1
Single-pass membrane protein with aspartate-rich tail 1a.
    
 0.914
LOC103030403
Mitochondrial calcium uptake family, member 3b.
     
 0.817
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.687
phb
Prohibitin.
     
 0.661
LOC103047478
Prohibitin.
     
 0.633
LOC103035142
Prohibitin.
     
 0.633
Afg3l2
AFG3-like AAA ATPase 2.
     
 0.604
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: medium (44%) [HD]