close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arafA-Raf proto-oncogene, serine/threonine kinase. (609 aa)    
Predicted Functional Partners:
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.978
map2k2
Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.
   
0.978
nras
NRAS proto-oncogene, GTPase.
   
 0.977
LOC103023536
Zgc:55558.
   
 0.971
LOC103038241
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.971
hras
HRas proto-oncogene, GTPase a.
   
 0.971
LOC103040103
HRas proto-oncogene, GTPase b.
   
 0.971
Rras
RAS related.
   
 0.953
rras2
RAS related 2.
   
 0.953
LOC103031239
Muscle RAS oncogene homolog.
   
 0.952
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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