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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K9S4_ASTMXMitochondrial fission regulator 2. (335 aa)    
Predicted Functional Partners:
hsd17b2
Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.573
LOC103038016
Matrix metallopeptidase 30.
     
 0.515
trps1
Trichorhinophalangeal syndrome I.
    
 
 0.478
cdc20
Cell division cycle 20 homolog.
   
 0.470
wdr18
WD repeat domain 18.
   
 0.470
cenpn
Centromere protein N.
   
 0.465
ndc80
NDC80 kinetochore complex component.
   
 
 0.462
ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
   
   0.445
birc5
Baculoviral IAP repeat containing 5a.
   
 
  0.437
BIRC5
Baculoviral IAP repeat containing 5.
   
 
  0.437
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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