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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K9U3_ASTMXDedicator of cytokinesis 3; Belongs to the DOCK family. (1945 aa)    
Predicted Functional Partners:
Crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.803
crk
V-crk avian sarcoma virus CT10 oncogene homolog.
    
 0.803
CRK
CRK proto-oncogene, adaptor protein.
    
 0.803
elmo2
Engulfment and cell motility 2.
    
 0.801
ENSAMXP00000032120
PH domain-containing protein.
    
 0.783
ENSAMXP00000050143
Engulfment and cell motility 3.
    
 0.783
LOC103028188
Engulfment and cell motility 1 (ced-12 homolog, C. elegans).
    
 0.783
ENSAMXP00000054363
Si:dkey-56f14.7.
    
 0.689
chek2
Checkpoint kinase 2.
     
 0.687
W5LNX5_ASTMX
Dedicator of cytokinesis 4b; Belongs to the DOCK family.
  
0.657
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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