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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KA34_ASTMXDystrobrevin. (670 aa)    
Predicted Functional Partners:
W5LMG4_ASTMX
Protein phosphatase 1, regulatory subunit 21.
    
   0.822
SNTA1
Syntrophin alpha 1.
    
 
 0.649
W5K1Z5_ASTMX
Syntrophin, beta 2.
    
 
 0.649
sntb1
Syntrophin, basic 1.
    
 
 0.649
LOC103035680
Si:dkey-34e4.1.
      
 0.564
C13h1orf226
Nitric oxide synthase 1 (neuronal) adaptor protein a.
      
 0.564
LOC103026217
Nitric oxide synthase 1 (neuronal) adaptor protein b.
      
 0.564
ENSAMXP00000027925
Uncharacterized protein.
    
   0.560
LOC103033990
Radial spoke head 3.
    
   0.560
ENSAMXP00000040049
Uncharacterized protein.
    
   0.560
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.