Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
W5KA75_ASTMXProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (552 aa)    
Predicted Functional Partners:
Rras
RAS related.
   
 0.933
rras2
RAS related 2.
   
 0.933
LOC103023536
Zgc:55558.
   
 0.931
LOC103031239
Muscle RAS oncogene homolog.
   
 0.931
LOC103038241
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.931
MRAS
Muscle RAS oncogene homolog.
   
 0.931
hras
HRas proto-oncogene, GTPase a.
   
 0.931
nras
NRAS proto-oncogene, GTPase.
   
 0.931
LOC103040103
HRas proto-oncogene, GTPase b.
   
 0.931
LOC103042331
FERM domain-containing protein.
   
  0.927
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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