Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ddx43DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. (730 aa)    
Predicted Functional Partners:
Srgap2
SLIT-ROBO Rho GTPase activating protein 2.
   
  
 0.856
rxylt1
Ribitol xylosyltransferase 1.
   
  
 0.797
rps11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
   
 0.787
atad2
ATPase family AAA domain containing 2.
   
 0.766
LOC103047530
Cyclin-dependent kinase 11B.
     
 0.755
Pus7l
Pseudouridine synthase 7 like.
   
 
 0.702
srp72
Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.
   
 
 0.682
LOC103033426
PR domain containing 9.
   
 
 0.670
LOC103031423
DND microRNA-mediated repression inhibitor 1.
    
 0.599
larp1
La ribonucleoprotein domain family, member 1.
    
 
 0.592
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: medium (46%) [HD]