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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddx43DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. (730 aa)    
Predicted Functional Partners:
sf3b1
Splicing factor 3b, subunit 1.
   
 0.655
Srgap2
SLIT-ROBO Rho GTPase activating protein 2.
   
  
 0.651
ENSAMXP00000033034
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.638
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.625
sf3b3
Splicing factor 3b, subunit 3.
   
 0.620
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 0.616
rxylt1
Ribitol xylosyltransferase 1.
      
 0.610
nop58
NOP58 ribonucleoprotein homolog (yeast).
  
 
 0.610
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.609
krr1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 0.600
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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