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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KAI8_ASTMXSolute carrier family 17 member 5. (448 aa)    
Predicted Functional Partners:
LOC103042153
Si:ch1073-513e17.1.
  
  
 
0.903
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 
 0.753
RIMS2-2
Regulating synaptic membrane exocytosis 2.
   
 
 0.753
wdfy2
WD repeat and FYVE domain containing 2.
      
 0.566
ENSAMXP00000053563
Uncharacterized protein.
     
 0.530
syt1
Synaptotagmin Ia.
   
 
 0.483
W5JZI3_ASTMX
C2 domain-containing protein.
   
 
 0.483
LOC103042251
Synaptotagmin IIa.
   
 
 0.483
LOC103029888
Synaptotagmin Vb.
   
 
 0.483
HECTD4
HECT domain E3 ubiquitin protein ligase 4.
    
 
 0.479
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.