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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdcd4Programmed cell death 4b. (470 aa)    
Predicted Functional Partners:
eif4a2
Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family.
   
 0.666
LOC103045638
Eukaryotic translation initiation factor 4A1A.
   
 0.666
ENSAMXP00000052586
Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.
   
 0.666
map3k2
Mitogen-activated protein kinase kinase kinase 2.
      
 0.499
gab1
GRB2-associated binding protein 1.
      
 0.440
reck
Reversion-inducing-cysteine-rich protein with kazal motifs.
      
 0.439
Pdcd7
Programmed cell death 7.
      
 0.431
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 0.426
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.