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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pkp4Plakophilin 4. (825 aa)    
Predicted Functional Partners:
LOC111196032
Uncharacterized protein.
   
 0.656
Ctnna2
Catenin (cadherin-associated protein), alpha 2.
   
 0.656
LOC103026956
Catenin (cadherin-associated protein), alpha 1.
   
 0.656
LOC103047521
Catenin alpha 2.
   
 0.656
ENSAMXP00000045943
Uncharacterized protein.
   
 0.656
LOC103034575
Catenin, beta 2.
    
 0.634
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.634
W5KDJ8_ASTMX
Junction plakoglobin b.
   
 0.616
LOC103045821
Junction plakoglobin a.
   
 0.616
LOC103034091
Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.571
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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