| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSAMXP00000051979 | HDAC2 | ENSAMXP00000051979 | ENSAMXP00000014739 | Amino_oxidase domain-containing protein. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.647 |
| ENSAMXP00000051979 | Hdac8 | ENSAMXP00000051979 | ENSAMXP00000013622 | Amino_oxidase domain-containing protein. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.647 |
| ENSAMXP00000051979 | LOC103036608 | ENSAMXP00000051979 | ENSAMXP00000051112 | Amino_oxidase domain-containing protein. | PHD finger protein 21Ab. | 0.546 |
| ENSAMXP00000051979 | W5KB31_ASTMX | ENSAMXP00000051979 | ENSAMXP00000004792 | Amino_oxidase domain-containing protein. | Uncharacterized protein. | 0.795 |
| ENSAMXP00000051979 | W5LQ84_ASTMX | ENSAMXP00000051979 | ENSAMXP00000022181 | Amino_oxidase domain-containing protein. | PHD finger protein 21Aa. | 0.546 |
| ENSAMXP00000051979 | kdm1a | ENSAMXP00000051979 | ENSAMXP00000035312 | Amino_oxidase domain-containing protein. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.415 |
| HDAC2 | ENSAMXP00000051979 | ENSAMXP00000014739 | ENSAMXP00000051979 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amino_oxidase domain-containing protein. | 0.647 |
| HDAC2 | KDM1B | ENSAMXP00000014739 | ENSAMXP00000049455 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine demethylase 1B. | 0.647 |
| HDAC2 | LOC103036608 | ENSAMXP00000014739 | ENSAMXP00000051112 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | PHD finger protein 21Ab. | 0.678 |
| HDAC2 | LOC103039919 | ENSAMXP00000014739 | ENSAMXP00000044363 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.647 |
| HDAC2 | Rest | ENSAMXP00000014739 | ENSAMXP00000046933 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | RE1-silencing transcription factor. | 0.646 |
| HDAC2 | W5KB31_ASTMX | ENSAMXP00000014739 | ENSAMXP00000004792 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Uncharacterized protein. | 0.708 |
| HDAC2 | W5LQ84_ASTMX | ENSAMXP00000014739 | ENSAMXP00000022181 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | PHD finger protein 21Aa. | 0.678 |
| HDAC2 | kdm1a | ENSAMXP00000014739 | ENSAMXP00000035312 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.870 |
| HDAC2 | maob | ENSAMXP00000014739 | ENSAMXP00000040090 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.647 |
| Hdac8 | ENSAMXP00000051979 | ENSAMXP00000013622 | ENSAMXP00000051979 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amino_oxidase domain-containing protein. | 0.647 |
| Hdac8 | KDM1B | ENSAMXP00000013622 | ENSAMXP00000049455 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine demethylase 1B. | 0.647 |
| Hdac8 | LOC103036608 | ENSAMXP00000013622 | ENSAMXP00000051112 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | PHD finger protein 21Ab. | 0.678 |
| Hdac8 | LOC103039919 | ENSAMXP00000013622 | ENSAMXP00000044363 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.647 |
| Hdac8 | Rest | ENSAMXP00000013622 | ENSAMXP00000046933 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | RE1-silencing transcription factor. | 0.646 |