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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itgb8Integrin beta; Belongs to the integrin beta chain family. (790 aa)    
Predicted Functional Partners:
vtn
Vitronectin b.
    
 0.971
LOC103043894
Vitronectin a.
    
 0.971
Ptk2
Protein tyrosine kinase 2aa; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.943
ENSAMXP00000033683
Integrin, alpha V; Belongs to the integrin alpha chain family.
    
 0.924
W5KRQ0_ASTMX
Laminin, gamma 3.
    
 0.920
lamc1
Laminin, gamma 1.
    
 0.920
ENSAMXP00000039033
Fibronectin 1b.
    
 0.918
W5KNT0_ASTMX
Si:ch211-241e1.3.
    
 0.916
LOC103024927
Laminin, alpha 3.
    
 0.916
LOC103026996
Laminin, beta 1a.
    
 0.913
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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