Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chukComponent of inhibitor of nuclear factor kappa B kinase complex. (755 aa)    
Predicted Functional Partners:
ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
   
 0.995
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.994
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.986
nfkb2
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).
    
 0.979
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
   
 0.978
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.978
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.977
Bcl10
BCL10 immune signaling adaptor.
   
 0.976
W5K777_ASTMX
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.
    
 0.974
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.974
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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