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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KBW6_ASTMXDynein, axonemal, heavy polypeptide 9 like. (2944 aa)    
Predicted Functional Partners:
ENSAMXP00000045847
DHC_N1 domain-containing protein.
 
     0.886
dctn2
Dynactin 2 (p50).
    
 0.798
LOC103030333
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
   
 0.768
LOC103047044
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
   
 0.768
dctn1
Dynactin 1b.
   
 0.756
LOC103029055
Dynactin domain-containing protein.
   
 0.756
W5K6I2_ASTMX
Dynein, cytoplasmic 2, light intermediate chain 1.
    
 0.701
Dnai1
Dynein, axonemal, intermediate chain 1, paralog 2.
  
 0.695
LOC103028862
Dynein light chain.
    
 0.677
LOC103028862-2
Dynein light chain 2, cytoplasmic.
    
 0.677
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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