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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceAngiotensin-converting enzyme. (1288 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
    
 0.944
SLC6A20
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.793
LOC103036504
Renin; Belongs to the peptidase A1 family.
      
 0.761
LOC103041285
Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.603
W5KMB6_ASTMX
Solute carrier family 14 member 2.
      
 0.579
nr3c2
Nuclear receptor subfamily 3, group C, member 2.
      
 0.577
ogg1
8-oxoguanine DNA glycosylase.
      
 0.577
cdx4
Caudal type homeobox 4.
      
 0.576
LOC103023628
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.568
LOC103025567
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.568
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.