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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbln4Cerebellin 4 precursor. (196 aa)    
Predicted Functional Partners:
LOC103026991
Stereocilin 1.
      
 0.574
W5KYP2_ASTMX
Tectorin alpha.
      
 0.557
leng1
Leukocyte receptor cluster (LRC) member 1.
      
 0.538
Tectb
Tectorin beta.
      
 0.445
Arhgap25
Rho GTPase activating protein 25.
      
 0.426
ENSAMXP00000035060
Uncharacterized protein.
      
 0.414
ENSAMXP00000036621
Uncharacterized protein.
      
 0.414
Unc5c
Unc-5 netrin receptor C.
   
  
 0.410
LOC103031663
Transcription factor 21.
      
 0.405
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.