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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KDI7_ASTMXUncharacterized protein; Belongs to the protein kinase superfamily. (392 aa)    
Predicted Functional Partners:
W5KHG8_ASTMX
Regulatory associated protein of MTOR, complex 1.
    
 0.786
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 0.757
LOC103033547
3-phosphoinositide dependent protein kinase 1b.
  
 
0.744
LOC103022926
3-phosphoinositide dependent protein kinase 1a.
  
 
0.743
mapkap1
MAPK associated protein 1.
    
 0.735
Prkdc
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.728
Smg1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 0.728
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.728
Rictor
RPTOR independent companion of MTOR, complex 2b.
    
 0.695
ENSAMXP00000042019
RPTOR independent companion of MTOR, complex 2 a.
    
 0.695
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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