close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KDQ7_ASTMXCD276 molecule. (283 aa)    
Predicted Functional Partners:
LOC103044351
CD28 molecule.
     
 0.718
LOC103047860
CD40 ligand; Belongs to the tumor necrosis factor family.
      
 0.579
LOC103029511
Ig-like domain-containing protein.
      
 0.568
LOC103041570
CD4-1 molecule.
    
 0.558
tnfrsf9
Tumor necrosis factor receptor superfamily, member 9b.
      
 0.489
LOC103036568
Tumor necrosis factor receptor superfamily, member 9a.
      
 0.489
ENSAMXP00000047619
CD40 molecule, TNF receptor superfamily member 5.
    
 0.471
W5KEH8_ASTMX
Ig-like domain-containing protein.
     
0.451
LOC111189321
V-set domain containing T cell activation inhibitor 1.
     
0.451
CD247
CD247 molecule.
      
 0.444
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.