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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KDS6_ASTMXDynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (456 aa)    
Predicted Functional Partners:
dctn2
Dynactin 2 (p50).
   
 0.909
DCTN6
Dynactin subunit 6.
    
 0.902
W5KZ67_ASTMX
Dynein, cytoplasmic 1, intermediate chain 2b.
   
 0.883
DYNC1I1
Dynein cytoplasmic 1 intermediate chain 1.
   
 0.883
LOC103032145
Dynein, cytoplasmic 1, intermediate chain 1.
   
 0.883
dync1i2
Dynein, cytoplasmic 1, intermediate chain 2a.
   
 0.883
dctn1
Dynactin 1b.
   
 0.877
LOC103029055
Dynactin domain-containing protein.
   
 0.877
LOC103036907
Actin related protein 1, centractin.
   
 0.865
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.863
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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