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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KDX2_ASTMXStromal antigen 2b. (1226 aa)    
Predicted Functional Partners:
smc3
Structural maintenance of chromosomes protein.
   
 0.987
smc1a
Structural maintenance of chromosomes protein.
   
 0.975
W5LMH3_ASTMX
Structural maintenance of chromosomes protein.
   
 0.972
LOC103030832
RAD21 cohesin complex component like 1.
   
 0.968
rad21
RAD21 cohesin complex component b.
   
 0.968
LOC103039334
RAD21 cohesin complex component a.
   
 0.968
espl1
Extra spindle pole bodies like 1, separase.
    
 0.965
W5KX19_ASTMX
PDS5 cohesin associated factor B.
   
 0.879
pds5a
PDS5 cohesin associated factor A.
   
 0.879
ENSAMXP00000051046
Structural maintenance of chromosomes protein.
   
 0.869
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.