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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103040528Protein kinase N2. (979 aa)    
Predicted Functional Partners:
LOC103031338
Ras homolog family member Cb.
   
 0.955
LOC103028705
Ras homolog gene family, member Aa.
   
 0.955
LOC103029431
Uncharacterized protein.
   
 0.955
LOC103035456
Ras homolog family member Ca.
   
 0.955
LOC103027457
Ras homolog gene family, member Ab.
   
 0.955
LOC103027669
Protein kinase N2.
  
  
 
0.901
LOC103022926
3-phosphoinositide dependent protein kinase 1a.
    
0.672
LOC103033547
3-phosphoinositide dependent protein kinase 1b.
    
0.672
RHOB
Ras homolog family member B.
   
 0.574
LOC103021440
Rho family GTPase 3.
   
 0.571
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.