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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103025130Phosphoinositide phospholipase C. (749 aa)    
Predicted Functional Partners:
INPP5A
Inositol polyphosphate-5-phosphatase A.
   
 
 0.914
Itpr1
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 
 0.910
Mtm1
Myotubularin 1.
     
 0.901
inpp1
Si:ch211-160o17.2.
     
  0.900
plce1
Phospholipase C, epsilon 1.
     
 
0.788
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
0.776
plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
0.776
pip4k2a
Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a.
   
 0.741
pip4k2c
Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a.
   
 0.741
LOC103035282
Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b.
   
 0.741
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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