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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103040934Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (511 aa)    
Predicted Functional Partners:
Ch25h
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.966
LOC103034249
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 0.965
W5LUH5_ASTMX
Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family.
   
 0.965
LOC103034469
Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family.
   
 0.965
LOC103045179
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
   
 0.965
LOC111194838
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.965
hsd3b1
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
   
 0.961
Hsd3b7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase.
   
 0.961
LOC103039880
Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3.
  
 
0.933
LOC103023184
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
 0.931
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.