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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KFJ0_ASTMXMothers against decapentaplegic homolog. (468 aa)    
Predicted Functional Partners:
smurf1
E3 ubiquitin-protein ligase.
    
 0.844
SMURF2
E3 ubiquitin-protein ligase.
    
 0.829
ENSAMXP00000050414
E3 ubiquitin-protein ligase.
    
 0.829
nedd4
E3 ubiquitin-protein ligase.
    
 0.726
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
    
 0.726
W5KYV8_ASTMX
Ring finger protein 111.
   
 0.725
rnf6
Ring finger protein (C3H2C3 type) 6.
   
 0.707
ENSAMXP00000040747
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.703
W5K2F8_ASTMX
E3 ubiquitin-protein ligase.
    
 0.694
wwp1
E3 ubiquitin-protein ligase.
    
 0.694
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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