Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5KFK3_ASTMXLactase-like a; Belongs to the glycosyl hydrolase 1 family. (569 aa)    
Predicted Functional Partners:
W5L834_ASTMX
Fibroblast growth factor receptor.
    
 0.740
fgf19
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.733
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
 0.723
gusb
Glucuronidase, beta.
    
 0.723
fgfr4
Fibroblast growth factor receptor 4.
    
 0.685
ENSAMXP00000048061
Fibroblast growth factor receptor.
    
 0.685
Fgfr3
Fibroblast growth factor receptor.
    
 0.685
W5LQK5_ASTMX
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
    
 0.681
glb1
Beta-galactosidase.
  
 
 0.677
gck
Phosphotransferase.
     
 0.658
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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