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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (546 aa)    
Predicted Functional Partners:
pard6a
Par-6 family cell polarity regulator alpha.
    
 0.994
PARD3
Par-3 family cell polarity regulator.
    
 0.988
LOC111193453
Par-6 family cell polarity regulator gamma a.
    
 0.985
LOC103026002
Par-6 family cell polarity regulator gamma b.
    
 0.985
pard6b
Par-6 partitioning defective 6 homolog beta (C. elegans).
    
 0.985
llgl1
LLGL scribble cell polarity complex component 1.
    
 0.981
llgl2
LLGL scribble cell polarity complex component 2.
    
 0.981
W5KW74_ASTMX
Sequestosome 1.
    
 0.946
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
0.924
W5KDE5_ASTMX
Erythrocyte membrane protein band 4.1 like 4B.
    
 0.921
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.