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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KG85_ASTMXAlkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (240 aa)    
Predicted Functional Partners:
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17.
      
 0.613
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
    
 
 0.593
LOC103021762
Neutral ceramidase.
    
 
 0.589
Sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
   
  
 0.588
asah1
N-acylsphingosine amidohydrolase (acid ceramidase) 1b; Belongs to the acid ceramidase family.
   
  
 0.587
ENSAMXP00000040343
Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis).
      
 0.565
ENSAMXP00000049111
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
   
  
 0.563
acer1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
0.546
LOC103040162
Zgc:158263.
    
 0.541
FCHSD2
FCH and double SH3 domains 2.
      
 0.534
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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