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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KGI5_ASTMXSolute carrier family 46 member 1. (252 aa)    
Predicted Functional Partners:
dhfr
Dihydrofolate reductase.
      
 0.721
mthfd1l
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.
      
 0.718
pde3b
Phosphodiesterase.
      
 0.666
LOC103038270
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
    0.633
LOC103035400
Adenosine kinase b.
      
 0.600
adk
Adenosine kinase a.
      
 0.600
slc19a1
Solute carrier family 19 member 1.
      
 0.575
LOC103042747
Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.572
ENSAMXP00000045240
Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      
 0.572
LOC103042073
Zgc:153031.
      
 0.572
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.