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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103024576Speckle type BTB/POZ protein like a. (392 aa)    
Predicted Functional Partners:
W5KX87_ASTMX
Cullin 3a; Belongs to the cullin family.
   
 0.990
cul3
Cullin 3b; Belongs to the cullin family.
   
 0.990
LOC111191049
Speckle type BTB/POZ protein.
  
  
 
0.960
sufu
Suppressor of fused homolog.
     
 0.936
Gli3
GLI family zinc finger 3.
   
 0.913
LOC103028990
GLI family zinc finger 2b.
   
 0.913
Gli1
GLI family zinc finger 1.
   
 0.913
gli2
GLI family zinc finger 2a.
   
 0.913
LOC103032629
Speckle type BTB/POZ protein like b.
  
  
 
0.900
LOC111194478
Cullin 1a; Belongs to the cullin family.
   
 0.823
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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