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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KHI0_ASTMXRetinoid X receptor, alpha a. (456 aa)    
Predicted Functional Partners:
W5KFT4_ASTMX
Nuclear receptor subfamily 1, group H, member 3.
   
0.891
LOC103043413
Nuclear receptor subfamily 1, group H, member 5.
   
0.794
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
0.794
W5LKA6_ASTMX
Nuclear receptor corepressor 1.
    
 0.774
Ncor2
Nuclear receptor corepressor 2.
    
 0.774
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.760
ncoa2
Nuclear receptor coactivator.
   
 0.743
Ncoa1
Nuclear receptor coactivator 1.
   
 0.743
W5KHP0_ASTMX
Nuclear receptor coactivator 3.
   
 0.737
LOC103026609
Uncharacterized protein.
   
 0.737
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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