close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1Signal-induced proliferation-associated 1. (936 aa)    
Predicted Functional Partners:
LOC103043765
RAP2A, member of RAS oncogene family b.
    
 0.592
Rap2b
RAP2B, member of RAS oncogene family.
    
 0.557
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1.
   
 0.541
LOC103022868
RAP1A, member of RAS oncogene family b.
    
 0.518
rap1b
RAP1B, member of RAS oncogene family.
    
 0.518
rap1a
RAP1A, member of RAS oncogene family a.
    
 0.518
LOC103032316
Neurexophilin 2b.
   
  
 0.516
LOC103033866
Non-specific serine/threonine protein kinase.
      
 0.515
rap2c
RAP2C, member of RAS oncogene family.
    
 0.480
LOC103024889
Neurexophilin; May be signaling molecules that resemble neuropeptides.
   
  
 0.476
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: very high (>100%) [HD]