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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KHP9_ASTMXNeuronal PAS domain protein 2. (842 aa)    
Predicted Functional Partners:
W5KS08_ASTMX
Aryl hydrocarbon receptor nuclear translocator-like 1b.
   
0.842
LOC103031232
Aryl hydrocarbon receptor nuclear translocator-like 1a.
   
0.842
arntl2
Aryl hydrocarbon receptor nuclear translocator-like 2.
  
0.838
LOC103044559
Cryptochrome circadian regulator 2.
   
 0.807
Sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 0.754
LOC103039742
Period circadian clock 2.
    
0.731
LOC103033595
Period circadian clock 1b.
    
0.731
Cry1
Cryptochrome circadian regulator 1b.
   
 0.724
LOC103034890
Cryptochrome circadian regulator 5.
   
 0.722
timeless
Timeless circadian clock.
   
 0.713
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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