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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGFLAMEGF like, fibronectin type III and laminin G domains. (970 aa)    
Predicted Functional Partners:
Dag1
Dystroglycan 1.
   
 0.817
katnal2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
    
 
 0.740
LOC103036564
Info leucine-rich repeat, immunoglobulin-like and transmembrane domains 3a.
    
 0.654
paip1
Poly(A) binding protein interacting protein 1.
      
 0.650
ENSAMXP00000039773
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.648
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
    
 0.629
kcnv2
Potassium channel, subfamily V, member 2a; Belongs to the potassium channel family.
    
 0.627
rps27a
Ribosomal protein S27a.
    
  0.626
ranbp3l
RAN binding protein 3 like.
      
 0.616
Rplp0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
   
 0.607
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.