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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enosf1Enolase superfamily member 1. (439 aa)    
Predicted Functional Partners:
Dph5
Diphthamide biosynthesis 5.
      
 0.669
Tyms
Thymidylate synthetase.
   
  
 0.592
ENSAMXP00000030065
Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting).
      
 0.580
Cep290
Centrosomal protein 290.
     
 0.571
Hps3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
      
 0.543
W5LJ64_ASTMX
Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.531
Ptk2
Protein tyrosine kinase 2aa; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.531
ptk2b
Protein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.531
ENSAMXP00000042789
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.531
armc9
Armadillo repeat containing 9.
      
 0.526
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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