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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dennd5bDENN/MADD domain containing 5B. (1246 aa)    
Predicted Functional Partners:
ENSAMXP00000038452
CHM Rab escort protein.
     
 0.628
RAB28
RAB28, member RAS oncogene family.
     
 0.606
LOC103036351
RAB6B, member RAS oncogene family b.
    
 
 0.584
Rab41
RAB41, member RAS oncogene family.
    
 
 0.584
LOC103024680
RAB6B, member RAS oncogene family a.
    
 
 0.584
rab6a
RAB6A, member RAS oncogene family.
    
 
 0.584
W5LPW0_ASTMX
Integrin alpha FG-GAP repeat containing 1.
      
 0.575
avl9
AVL9 homolog (S. cerevisiase).
      
 0.573
sgsm3
Small G protein signaling modulator 3.
      
 0.497
rpf1
Ribosome production factor 1 homolog.
      
 0.481
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.