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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpp3Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (726 aa)    
Predicted Functional Partners:
atp23
Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family.
      
 0.693
W5K581_ASTMX
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
      
 0.631
LOC103047839
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
      
 0.631
CPQ
Carboxypeptidase Q.
      
 0.574
ENSAMXP00000027382
TROVE domain-containing protein.
      
 0.573
Tep1
DUF4062 domain-containing protein.
      
 0.573
mipep
Mitochondrial intermediate peptidase.
   
  
 0.573
ENSAMXP00000030088
Telomerase-associated protein 1.
      
 0.573
ENSAMXP00000037339
Si:ch73-1a9.4.
   
  
 0.573
ENSAMXP00000037701
RING-type domain-containing protein.
      
 0.573
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.