close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103036512Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (671 aa)    
Predicted Functional Partners:
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
    
 0.947
ENSAMXP00000041728
Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.
   
 0.916
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.911
dnm1l
Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
  
  
 
0.901
ENSAMXP00000039227
Cyclin G associated kinase.
   
 0.884
LOC103042026
Mitochondrial elongation factor 2.
    
 
 0.863
mff
Zgc:110130.
   
 0.784
Prkn
Parkin RBR E3 ubiquitin protein ligase.
    
 0.723
pink1
PTEN induced kinase 1.
    
 0.715
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
   
 0.690
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: medium (50%) [HD]