close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntn4Netrin 4. (585 aa)    
Predicted Functional Partners:
Unc5a
Unc-5 netrin receptor A.
     
 0.766
Unc5c
Unc-5 netrin receptor C.
     
 0.693
LOC103031419
Neogenin 1a.
   
 0.677
Dcc
DCC netrin 1 receptor.
   
 0.668
W5LIV1_ASTMX
Neogenin 1b.
   
 0.668
igdcc4
Immunoglobulin superfamily, DCC subclass, member 4.
   
 0.604
ENSAMXP00000037358
Unc-5 netrin receptor Da.
     
 0.600
Unc5d
Unc-5 netrin receptor Db.
     
 0.600
unc5b
Unc-5 netrin receptor B.
      
 0.515
Ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.484
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.