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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Orai2ORAI calcium release-activated calcium modulator 2. (251 aa)    
Predicted Functional Partners:
stim2
Stromal interaction molecule 2b.
    
 0.990
LOC103031161
Tromal interaction molecule 2a.
    
 0.985
ENSAMXP00000030762
Stromal interaction molecule 1a.
    
 0.981
LOC103031227
ORAI calcium release-activated calcium modulator 1b.
  
  
 
0.901
orai1
ORAI calcium release-activated calcium modulator 1a.
  
  
 
0.901
stim1
Stromal interaction molecule 1b.
    
 0.897
LOC103025180
Transient receptor potential cation channel, subfamily C, member 6a; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.487
trpc1
Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.433
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.